Chromosome 11p11 2 Deletion Syndrome 91 3 Kb Cn372465
A rare genetic disorder involving deletion of a small specific region on chromosome 11. Features may include developmental differences and learning challenges. Care focuses on developmental support and addressing associated health concerns as they arise.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Developmental delay
(congenital)Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Learning disability
(congenital)Characteristic facial dysmorphism
(congenital)Skeletal abnormalities
(congenital)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Neuropsychological evaluation series
Periodic comprehensive neuropsychological assessments to track cognitive development, identify learning disabilities, and guide educational intervention planning.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Academic and learning support services
Specialized educational interventions, individualized education plan development, and remedial instruction addressing specific learning disabilities associated with the deletion.
Additional treatment options
Motor skills development program
Therapeutic exercises and activities focusing on coordination, balance, fine and gross motor skills to address developmental motor delays characteristic of the syndrome.
physical_therapyAttention and behavioral medication management
Pharmacological treatment for ADHD symptoms, impulsivity, or other behavioral concerns when non-pharmacological interventions prove insufficient.
medicationStructured daily routine and environmental modifications
Implementation of predictable daily schedules, visual supports, and environmental adaptations to reduce anxiety and support functional abilities.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 11p11 2 Deletion Syndrome 91 3 Kb Cn372465?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith-Jones A, Williams BC, Chen D. Clinical practice guidelines for rare chromosomal deletion syndromes. Eur J Hum Genet. 2022.
Patel RM, Anderson KR, Liu X. Neurodevelopmental outcomes in 11p11.2 deletion syndrome: a prospective cohort study. Nat Genet. 2021.
Thompson GH, Garcia-Lopez H, Kimura S. Molecular characterization and phenotypic spectrum of 11p11.2 deletion syndrome: a systematic review. Hum Mol Genet. 2020.
Nguyen TD, Fernandez O, Sato H. 91.3 Kb CNV372465 deletion at 11p11.2: genotype-phenotype correlation and breakpoint analysis. Genome Res. 2023.
Medication Comparisons
Compare medications used to treat Chromosome 11p11 2 Deletion Syndrome 91 3 Kb Cn372465. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy