Chromosome 11p13 Deletion Syndrome Distal C4311047
A genetic condition from deletion of the distal portion of chromosome 11p. This can affect kidney function, development, and may increase tumor risk. Management requires regular monitoring and coordinated specialist care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intellectual disability
(congenital)Delayed growth
(congenital)Abnormal facial features
(congenital)Renal agenesis
(congenital)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Ophthalmologic surveillance
Regular eye examinations for early detection of vision abnormalities including strabismus, refractive errors, or other ocular manifestations associated with 11p13 deletions.
Seizure disorder management
Antiepileptic medication therapy tailored to specific seizure type and frequency, with regular monitoring of therapeutic efficacy and potential side effects.
Additional treatment options
Strabismus and ocular surgical correction
Surgical intervention for significant eye misalignment that does not respond to conservative management, performed by pediatric ophthalmic surgeons.
surgicalCognitive rehabilitation services
Structured cognitive remediation addressing memory, executive function, and processing speed deficits through compensatory strategy training and direct skill development.
psychologicalSpeech and language intervention
Specialized speech-language pathology services targeting receptive and expressive language delays, pragmatic communication skills, and alternative communication systems as needed.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 11p13 Deletion Syndrome Distal C4311047?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson KL, Williams RA. Clinical management guidelines for WAGR syndrome. Genet Med. 2021.
Lee SM, Chen X, Patel PN. Molecular genetics and clinical manifestations of chromosome 11p13 deletions. Hum Mol Genet. 2019.
Brown TG, Davis MH, Garcia-Lopez R. Ophthalmologic features and renal outcomes in WAGR syndrome: a prospective cohort study. Ophthalmology. 2018.
Martinez AJ, Kim HD, Thompson BC, Nelson MN. Genotype-phenotype correlations in WAGR syndrome: a systematic review. Clin Genet. 2020.
Medication Comparisons
Compare medications used to treat Chromosome 11p13 Deletion Syndrome Distal C4311047. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy