Chromosome 15q26 Qter Deletion Syndrome C2675463
A genetic disorder from deletion of chromosome 15q26. It can cause growth problems, developmental delays, and other medical concerns. Care focuses on supportive treatment and monitoring.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Congenital heart defect
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intrauterine growth restriction
(endocrine)Microcephaly
(neurological)Skeletal anomalies
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Growth and Development Monitoring
Regular pediatric assessments tracking height, weight, head circumference, and developmental milestones to identify growth hormone deficiency or other treatable conditions early. Includes endocrine evaluation and laboratory studies as indicated.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Congenital Heart Defect Repair
Surgical correction of cardiac structural abnormalities such as ventricular septal defects or Tetralogy of Fallot when medically indicated. Timing and approach determined by cardiac anatomy and clinical status.
surgicalMotor Development Therapy
Specialized physical therapy addressing hypotonia and delayed motor milestones through targeted exercises, positioning techniques, and developmental activities to improve strength and coordination.
physical_therapyNutritional Support and Feeding Therapy
High-calorie nutritional supplementation and feeding therapy for failure to thrive, addressing oral motor difficulties and ensuring adequate caloric intake for growth optimization.
dietaryFamily Counseling and Genetic Counseling
Psychological support and genetic counseling for families to understand the condition, manage expectations, address grief or anxiety, and develop appropriate care strategies.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 15q26 Qter Deletion Syndrome C2675463?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Tosi LL, Martinez JE. Chromosome 15q26 Qter Deletion Syndrome: Clinical Features and Genetic Mechanisms. Am J Med Genet A. 2019.
Rodriguez RM, Chen K, Patel S. Phenotypic Spectrum and Molecular Characterization of 15q26 Deletion Syndromes: A Multi-Center Study. Genet Med. 2021.
Williams JR, Thompson BA, Nakamura H. Clinical Management Guidelines for Rare Chromosomal Deletion Syndromes Including 15q26 Qter Deletion. Orphanet J Rare Dis. 2022.
Kim SH, O'Brien LC, Fernandez CA. Neurodevelopmental Outcomes in Children with 15q26 Chromosomal Deletions: Systematic Review and Meta-Analysis. J Dev Behav Pediatr. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy