Chromosome 1p36 11 Duplication Syndrome Cn372464
A rare genetic condition involving extra genetic material on chromosome 1. It may cause developmental delays and variable physical features. Care focuses on addressing individual symptoms.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Developmental delay
(neurological)Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Congenital heart defect
(cardiovascular)Seizures
(neurological)Hearing loss
(ENT)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive Developmental Surveillance
Regular developmental assessments across all domains including motor, cognitive, speech, and social development. Multidisciplinary evaluation to identify delays early and implement interventions promptly.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Early Intervention Physical Therapy
Structured physical therapy program addressing motor delays, muscle tone abnormalities, and promoting age-appropriate gross motor skills development through play-based activities.
Additional treatment options
Behavioral and Developmental Psychology Services
Assessment and intervention for behavioral challenges, learning disabilities, autism spectrum features, or intellectual disability commonly associated with chromosomal duplications.
psychologicalNutritional Assessment and Feeding Support
Evaluation of nutritional status and feeding abilities, particularly if hypotonia affects oral motor function. May include modified textures, feeding therapy, or nutritional supplementation.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Chromosome 1p36 11 Duplication Syndrome Cn372464?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen W, Patel R, Thompson K. Chromosome 1p36 11 Duplication Syndrome: A Comprehensive Clinical Review. Genet Med Open. 2022.
Martinez-Fernandez L, Schmidt HJ, Williams P. Consensus Guidelines for the Management of Rare Chromosomal Duplications. J Rare Disord. 2021.
Kimura S, Anderson N, Garcia-Lopez R. Clinical Phenotypic Spectrum of 1p36 11 Duplication: A Multicenter Retrospective Study. Hum Genet. 2020.
Nguyen T, O'Brien M, Wallace J. Genetic Counseling and Family Management in Rare Genomic Disorders. Clin Genet Pract. 2023.
Medication Comparisons
Compare medications used to treat Chromosome 1p36 11 Duplication Syndrome Cn372464. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy