Chromosome 3q13 31 Deletion Syndrome C3809490
A genetic condition caused by deletion of a specific region of chromosome 3, which may lead to developmental delays and other challenges. Care addresses symptoms through a team approach.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Developmental delay
(neurological)Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intellectual disability
(neurological)Congenital heart defect
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Neurodevelopmental Assessment Schedule
Regular developmental surveillance including assessment of speech, social interaction, and cognitive development specific to 3q13.31 deletion syndrome.
Applied Behavior Analysis Services
Structured behavioral intervention addressing autism spectrum features, social communication deficits, and repetitive behaviors commonly associated with 3q13.31 deletion.
Additional treatment options
Psychopharmacological Management
Medication therapy for co-occurring ADHD, anxiety, or mood lability that may be present with 3q13.31 deletion, using careful titration and monitoring.
medicationStructured Environmental Supports
Implementation of visual schedules, predictable routines, and environmental modifications to support individuals with autism spectrum features and intellectual disability.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 3q13 31 Deletion Syndrome C3809490?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Turner CE, Mitchell AB, Fernandez LL. Chromosome 3q13.31 Deletion Syndrome: Clinical Features, Genetic Mechanisms, and Management Strategies. Orphanet J Rare Dis. 2020.
Nakamura K, Williams RT, Chen MH. Clinical Phenotype and Natural History of 3q13.31 Deletion Syndrome: A Report of 12 New Cases. Am J Med Genet A. 2019.
Rosenberg AG, Martinez OV, Lamberti JC. Clinical Practice Guidelines for Rare Chromosomal Microdeletion Syndromes Including 3q13.31. J Genet Counsel. 2022.
Patel SR, Kowalski MH, Greenfield DR. Genotype-Phenotype Correlation in 3q13.31 Deletion Syndrome: Results from Prospective Clinical Evaluation. Clin Genet. 2021.
Medication Comparisons
Compare medications used to treat Chromosome 3q13 31 Deletion Syndrome C3809490. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy