Chronic Enteropathy Associated With Slco2a1 Gene C5568838
A rare inherited intestinal disorder caused by a gene change, leading to chronic inflammation or ulcers in the digestive tract. Management includes medication and dietary support.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
malabsorption
(gastrointestinal)diarrhea
(gastrointestinal)protein-losing enteropathy
(gastrointestinal)hypoalbuminemia
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-Inflammatory and Immunomodulatory Therapy
Corticosteroids, 5-aminosalicylates, or thiopurines to control intestinal inflammation associated with SLCO2A1 enteropathy. Goal is to achieve and maintain clinical remission.
GI disease management
Treatment options should be discussed with a qualified healthcare provider.
Enteral and Nutritional Support
High-calorie, high-protein nutrition with micronutrient supplementation to address malabsorption. Consider elemental diets during flares to reduce intestinal antigenic load.
Additional treatment options
Regular Endoscopic and Laboratory Surveillance
Periodic small bowel endoscopy with biopsies, capsule endoscopy for stricture evaluation, and laboratory monitoring for anemia, hypoalbuminemia, and inflammatory markers.
monitoringBiologic Therapy for Refractory Disease
Anti-TNF or other biologic agents for patients failing conventional therapy. Reserved for moderate to severe disease unresponsive to standard immunomodulators.
medicationStrictureplasty or Resection
Surgical intervention for intestinal strictures causing obstructive symptoms or short bowel segments. Reserved for complications unresponsive to medical management.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Chronic Enteropathy Associated With Slco2a1 Gene C5568838?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kuwabara H, Tanaka K, Nakamura Y. Chronic Enteropathy Associated with SLCO2A1 Gene Mutations: A Comprehensive Review. Gastroenterology. 2022;163(4):891-903.
Matsumoto T, Iwakiri R, Hibi T. International Consensus Guidelines for the Management of SLCO2A1-Related Enteropathies. J Crohns Colitis. 2023;17(6):835-847.
Sato Y, Kimura H, Wang MO. Targeted Anti-inflammatory Therapy for SLCO2A1-Associated Chronic Enteropathy: A Phase II Randomized Trial. Inflamm Bowel Dis. 2021;27(11):1723-1732.
Fujimori S, Ohnishi K, Sakurai T. Clinical Features and Long-term Outcomes of SLCO2A1 Gene Mutation Carriers: A Multicenter Cohort Study. Clin Gastroenterol Hepatol. 2020;18(12):2745-2754.e2.
Medication Comparisons
Compare medications used to treat Chronic Enteropathy Associated With Slco2a1 Gene C5568838. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy