Chronic Kidney Disease Progression Cn380059
The gradual worsening of chronic kidney disease, where kidney function declines over time. Close monitoring and controlling underlying conditions can help slow progression.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Uremic bleeding
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Increasing serum creatinine
(renal)Decreasing estimated GFR
(renal)Worsening proteinuria
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Disease progression tracking with imaging and labs
Serial imaging studies and laboratory markers to monitor kidney function trajectory and identify accelerating decline requiring intervention escalation.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Comprehensive risk factor modification
Aggressive management of diabetes, hypertension, hyperlipidemia, and avoidance of nephrotoxic medications to slow functional decline.
Additional treatment options
Advanced CKD dietary counseling
Increasingly restrictive dietary management including protein moderation, phosphorus binding strategies, and potassium management as function declines.
dietaryPreparation for renal replacement therapy
Multidisciplinary preparation including dialysis access creation, education about treatment options, and evaluation for kidney transplant candidacy.
procedureSmoking cessation and toxin avoidance
Complete smoking cessation and avoidance of environmental nephrotoxins including certain medications and contrast agents to preserve remaining renal function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Chronic Kidney Disease Progression Cn380059?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kidney Disease Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl. 2024.
Chen TK, Knicely DH, Grams ME. Chronic Kidney Disease Diagnosis and Management: A Review. JAMA. 2019.
Heerspink HJL, Stefansson BV, Correa-Rotter R, et al. Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2020.
Palmer SC, Telini MM, Navaneethan SD, Craig JC. Urinary Sodium Excretion and Kidney Disease Progression: Meta-Analysis. Am J Kidney Dis. 2018.
Medication Comparisons
Compare medications used to treat Chronic Kidney Disease Progression Cn380059. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy