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Ciliary Dyskinesia Primary 48 Without Situs Inversus C5774214

Published: July 22, 2026Updated: August 20, 2026

A genetic disorder affecting tiny hair-like structures called cilia. It causes chronic respiratory and ear infections. Treatment involves managing infections and airway clearance.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
J98.9
ICD-11
CA00.0
Body system
respiratory
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Neonatal respiratory distress

Chronic cough

(respiratory)

Shortness of breath or cough

(respiratory)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Recurrent sinusitis

(respiratory)

Bronchiectasis

(respiratory)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Positive Expiratory Pressure Therapy

Devices providing resistance during exhalation to maintain open airways and promote mucus movement toward larger bronchi for expectoration.

physical_therapy
2

Respiratory therapy and management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Chronic Suppressive Antibiotic Therapy

Rotating antibiotic courses to suppress bacterial colonization and prevent acute exacerbations in chronic respiratory disease.

medication

Additional treatment options

Imaging and Spirometry Monitoring

Periodic CT imaging and pulmonary function testing to detect structural changes and track functional decline over time.

monitoring

Nasal Saline Irrigation

Daily nasal rinsing with isotonic or hypertonic saline solutions to improve mucociliary function and reduce sinonasal symptoms.

complementary

Bronchiectasis Resection

Targeted surgical removal of severely damaged lung segments in cases of localized bronchiectasis with recurrent infections unresponsive to medical therapy.

surgical

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Ciliary Dyskinesia Primary 48 Without Situs Inversus C5774214?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Werner C, Bush A, Robinson P, et al. European Respiratory Society guidelines for the diagnosis and management of primary ciliary dyskinesia. Eur Respir J. 2023.

guideline2023
2

Leigh MW, Horani A, Kinghorn B, et al. Genetics and biology of primary ciliary dyskinesia. Paediatr Respir Rev. 2021.

review2021
3

Kobbernagel HE, Nielsen KG, Pressler T, et al. Efficacy and safety of azithromycin maintenance therapy in primary ciliary dyskinesia: a randomised controlled trial. Thorax. 2022.

clinical_trial2022
4

Santharam V, Fenton SE, McManus R, et al. Airway clearance techniques in patients with primary ciliary dyskinesia: a systematic review and meta-analysis. Respir Med. 2020.

meta_analysis2020

Medication Comparisons

Compare medications used to treat Ciliary Dyskinesia Primary 48 Without Situs Inversus C5774214. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy