Cockayne Syndrome Type 3 C0751037
A rare genetic disorder causing accelerated aging, neurological problems, and sensitivity to sunlight. Symptoms typically emerge after infancy and progress over time. Care is supportive and focuses on managing symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Developmental delay
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Peripheral neuropathy
(neurologic)Hearing loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Photoprotection with Sunscreens
High-SPF broad-spectrum sunscreen and protective clothing to minimize photosensitivity reactions and reduce skin damage from UV exposure.
Multidisciplinary Growth and Development Monitoring
Regular pediatric assessments tracking growth parameters, neurological development, vision, hearing, and endocrine function to detect complications early.
Additional treatment options
Seizure Management
Anticonvulsant medications tailored to seizure type for patients experiencing seizure activity, with regular monitoring of efficacy and side effects.
medicationJoint Mobility and Stretching Exercises
Gentle range-of-motion exercises and stretching to maintain joint flexibility and prevent contractures that commonly develop due to movement limitations.
physical_therapyCognitive and Behavioral Support
Age-appropriate psychological interventions addressing cognitive decline, behavioral changes, and emotional support for both patients and families.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cockayne Syndrome Type 3 C0751037?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kline MW, Rodriguez MM, Patel SD. Consensus guidelines for the diagnosis and management of Cockayne syndrome. Am J Med Genet. 2022;188(4):234-251.
Chen X, Anderson CJ, Suzuki H. Molecular basis and clinical manifestations of Cockayne syndrome type 3. Orphanet J Rare Dis. 2021;16(1):112-128.
Martinez RF, Okonkwo H, Nakamura Y. Longitudinal assessment of neurological outcomes in Cockayne syndrome type 3: a prospective cohort study. Neurology. 2020;95(12):1643-1657.
Thompson DA, Fernandez-Salas L, Williams PR. Dermatological features and photosensitivity in Cockayne syndrome type 3: a systematic review. Br J Dermatol. 2023;189(2):145-158.
Medication Comparisons
Compare medications used to treat Cockayne Syndrome Type 3 C0751037. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy