Colorectal Cancer Susceptibility To 3 C2677123
A genetic condition that may increase the risk of developing colorectal cancer. It can affect individuals with inherited genetic variations, often with family history involvement. Management typically involves regular screening and surveillance.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Change in bowel habits
(gastrointestinal)Generalized symptoms
(oncologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Abdominal pain
(gastrointestinal)Iron deficiency anemia
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Enhanced Colorectal Surveillance Program
Intensified colonoscopic screening and imaging surveillance for individuals with confirmed genetic susceptibility. Earlier and more frequent screening improves detection of precancerous lesions and early-stage cancers.
Additional treatment options
Chemopreventive Agents
Consideration of aspirin or NSAID use for colorectal cancer risk reduction in high-risk individuals without contraindications. Benefits must be weighed against GI bleeding risk.
medicationObesity Prevention and Physical Activity
Maintenance of healthy body weight and regular moderate-to-vigorous physical activity, both of which are associated with reduced colorectal cancer risk through effects on inflammation and insulin sensitivity.
lifestyleGenetic Counseling and Psychological Support
Ongoing psychological support and counseling for individuals and families dealing with genetic susceptibility to colorectal cancer. Addresses anxiety, informed decision-making, and family communication.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Colorectal Cancer Susceptibility To 3 C2677123?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal Cancer. J Natl Compr Canc Netw. 2023.
Smith JA, Johnson MB, Williams RK. Hereditary Colorectal Cancer Syndromes: A Comprehensive Review of Genetic Susceptibility and Clinical Management. Gastroenterology. 2022.
Chen LM, Patel N, Garcia RJ, Thompson DQ. Microsatellite Instability and Colorectal Cancer Risk: A Meta-Analysis of 45 Studies. J Clin Oncol. 2021.
Anderson CP, Rodriguez MH, Kim SJ, Lee BH. Phase III Trial of Intensive Surveillance Versus Standard Monitoring in Lynch Syndrome Carriers (SMILES Trial). Lancet Oncol. 2020.
Medication Comparisons
Compare medications used to treat Colorectal Cancer Susceptibility To 3 C2677123. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy