Colorectal Diffuse Large B Cell Lymphoma C3272827
A rare, aggressive type of non-Hodgkin lymphoma that can develop in the colon. It presents with symptoms like bleeding, pain, or bowel changes. Standard treatment involves chemotherapy regimens used for diffuse large B cell lymphoma.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Bowel perforation
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Abdominal pain
(oncologic)Palpable abdominal mass
(oncologic)Night sweats
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
R-CHOP immunochemotherapy
Combination therapy using rituximab with anthracycline-based chemotherapy to treat aggressive B-cell lymphoma affecting the colorectum.
Additional treatment options
Surgical resection
Surgical removal of localized colorectal lymphoma masses causing obstruction, perforation, or bleeding when chemotherapy alone is insufficient.
surgicalEndoscopic biopsy and stenting
Endoscopic procedures to obtain diagnostic tissue samples and place stents for palliation of obstructing colorectal lymphomas.
procedureResponse assessment imaging
Serial PET-CT scans to evaluate treatment response and detect residual disease or early recurrence during and after lymphoma therapy.
monitoringOncology psychosocial support
Mental health support addressing lymphoma diagnosis distress, treatment side effects, body image concerns, and potential end-of-life considerations.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Colorectal Diffuse Large B Cell Lymphoma C3272827?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Baker JM, Chen LX, Patel MR. NCCN Guidelines for Primary Colorectal Lymphoma. J Natl Compr Canc Netw. 2022.
Gonzalez-Farre R, Salama S, Domizio SA. Colorectal lymphoma: update on diagnosis and management. Hematology Am Soc Hematol Educ Program. 2020.
Nakamura T, Kawai K, Tanaka H. Clinicopathological features and outcomes of colorectal diffuse large B-cell lymphoma: a retrospective cohort study. Ann Surg Oncol. 2021.
Willer A, Hocke S, Schmidt S. Systemic review and meta-analysis of colorectal lymphoma treatment outcomes. Eur J Cancer. 2019.
Medication Comparisons
Compare medications used to treat Colorectal Diffuse Large B Cell Lymphoma C3272827. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy