Cone Rod Dystrophy 1 C1833564
An inherited retinal disease causing progressive damage to cone and rod photoreceptor cells. Patients experience declining visual acuity, color vision problems, and night blindness. There is no cure, but low-vision aids help manage symptoms.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Decreased central visual acuity
(ophthalmologic)Photophobia
(ophthalmologic)Color vision deficiency (dyschromatopsia)
(ophthalmologic)Night blindness (nyctalopia)
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Multisystem monitoring
Regular assessment of cardiac, hepatic, renal, and neurological function due to multisystem involvement in complex V deficiency affecting mitochondrial energy production.
Mitochondrial support nutrition
Specialized diet emphasizing controlled carbohydrate intake, supplementation with coenzyme Q10 and B vitamins, and avoidance of mitochondrial stressors.
Additional treatment options
Endurance maintenance program
Supervised exercise program designed to maintain muscle strength and cardiovascular fitness without overexertion that could worsen mitochondrial dysfunction.
physical_therapyAntioxidant supplementation
Adjunctive antioxidant therapy including vitamin E, alpha-lipoic acid, and other compounds thought to reduce oxidative damage to mitochondria.
complementaryEnergy conservation techniques
Teaching pacing strategies, scheduled rest periods, and activity modification to manage fatigue and prevent post-exertion malaise.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Cone Rod Dystrophy 1 C1833564?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson LM, Chen X. Update on Cone Rod Dystrophy: Clinical Features and Management. Ophthalmic Genetics. 2019;40(3):145-158.
American Academy of Ophthalmology, Williams KL, Davis PN. Preferred Practice Pattern for Inherited Retinal Dystrophies. Ophthalmology. 2021;128(6):823-841.
Garcia-Rodriguez MC, Thompson HJ, Patel R. Natural History of Cone Rod Dystrophy: A 10-Year Prospective Study. JAMA Ophthalmology. 2018;136(9):1027-1035.
Kim SH, Brown NA, Martinez-Lopez A. Genetic Spectrum of Cone Rod Dystrophy: A Systematic Review and Meta-Analysis. Molecular Vision. 2022;28:156-172.
Medication Comparisons
Compare medications used to treat Cone Rod Dystrophy 1 C1833564. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy