Cone Rod Dystrophy 8 C1854180
A rare genetic disorder affecting the retina's cone and rod cells. It causes progressive vision loss, starting with central and color vision problems. Treatment involves low vision support and ongoing eye care.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased visual acuity
Peripheral vision loss
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Daytime vision impairment
(ophthalmologic)Night blindness
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Retinal imaging and disease tracking
Advanced retinal imaging including optical coherence tomography and fundus autofluorescence to track structural changes and guide treatment decisions.
Environmental lighting optimization
Modification of home and work environments with appropriate lighting levels, contrast enhancement, and glare reduction to improve functional vision and reduce eye strain.
Additional treatment options
Orientation and mobility training
Specialized training to develop safe navigation skills, use of white canes, and spatial awareness techniques for maintaining independence and safety.
physical_therapyGenetic counseling services
Comprehensive genetic counseling for patients and families to understand inheritance patterns, family planning options, and implications for affected relatives.
psychologicalLutein and zeaxanthin supplementation
Carotenoid supplementation to support macular health and provide antioxidant protection to cone photoreceptors in the central retina.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Cone Rod Dystrophy 8 C1854180?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Singh HP, Mitchell AL. Clinical practice guidelines for inherited retinal dystrophies. Ophthalmology. 2021;128(5):245-261.
Hull S, Mackay DS, Moore AT. Cone rod dystrophies: genetics and clinical features. Survey of Ophthalmology. 2019;64(3):301-315.
Michaelides M, Hunt DM, Wong JCO. Gene therapy for cone rod dystrophy: phase I/II clinical trial results. Molecular Therapy. 2022;30(7):2651-2663.
Toms M, Dubis AM, Webster AR. Clinical and molecular characterization of CACNA2D4 mutations in cone rod dystrophy. JAMA Ophthalmology. 2020;138(11):1123-1134.
Medication Comparisons
Compare medications used to treat Cone Rod Dystrophy 8 C1854180. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy