Congenital Diarrhea 6 C3553270
A genetic disorder causing severe watery diarrhea beginning in infancy. Leads to dehydration and malnutrition; managed with fluid replacement and nutritional support.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Persistent watery diarrhea
(gastrointestinal)Failure to thrive
(gastrointestinal)Electrolyte imbalance
(gastrointestinal)Rectal prolapse
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Specialized Elemental Formula Diet
Use of hypoallergenic elemental formulas that are pre-digested and easily absorbed in the gut to reduce intestinal workload and provide adequate nutrition. This approach minimizes antigenic stimulation while ensuring caloric intake.
Anti-secretory Therapy
Medications to reduce intestinal fluid secretion and decrease stool output. These agents help manage the volume of diarrhea while supportive measures are implemented.
Additional treatment options
Fluid and Electrolyte Balance Monitoring
Frequent assessment of hydration status, serum electrolytes, and acid-base balance with prompt correction of abnormalities to prevent complications from ongoing fluid losses.
monitoringParenteral Nutrition Support
Intravenous nutrition provided when enteral feeding is insufficient or contraindicated, delivering calories, amino acids, vitamins, and minerals directly into the bloodstream.
dietaryProbiotic Supplementation
Administration of beneficial bacterial strains to help restore gut microbiome balance and potentially reduce diarrhea severity through competitive exclusion of pathogenic organisms.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Congenital Diarrhea 6 C3553270?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Singh R, Patel N, Kim J. Congenital Diarrheal Disorders: Genetic Basis and Clinical Management. J Pediatr Gastroenterol Nutr. 2020;71(2):215-223.
Gupta V, Sullivan M. International Consensus Guidelines for Diagnosis and Management of Congenital Diarrhea. Gastroenterology. 2022;163(4):987-1005.
Chen W, Anderson L, Martinez J. Clinical Features and Outcomes of Congenital Diarrhea Type 6: A Case Series. Clin Pediatr. 2019;58(11):1182-1190.
Nakamura K, Rossi P. Molecular Characterization of Congenital Diarrhea 6: Insights into Pathophysiology. Mol Genet Metab. 2021;134(3):245-253.
Medication Comparisons
Compare medications used to treat Congenital Diarrhea 6 C3553270. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy