Curly Hair Acral Keratoderma Caries Syndrome C1843291
A rare genetic syndrome featuring curly hair, thickened skin on hands and feet, and increased tooth decay. Usually present from early childhood. Management focuses on skin care and dental monitoring.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Enhanced dental hygiene regimen
Comprehensive oral care including brushing, flossing, and fluoride mouthwash to manage caries component of the syndrome. Regular dental check-ups and professional cleanings.
Professional dental interventions
Regular dental assessments with fluoride treatments, sealants as appropriate, and prompt treatment of cavities. Dental professionals can provide targeted caries prevention strategies.
Additional treatment options
Topical keratolytic agents
Application of salicylic acid or urea-based creams to affected acral skin areas to reduce hyperkeratosis. Regular application as directed helps soften and remove thickened skin.
medicationSpecialized hair care regimen
Gentle hair care practices using moisturizing shampoos and conditioners designed for curly hair. Avoiding harsh chemical treatments and heat styling that may damage hair.
lifestyleCaries-reducing dietary modifications
Reducing sugar intake and frequency of snacking, increasing water consumption, and incorporating calcium-rich foods. Dietary counseling to support dental health.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Curly Hair Acral Keratoderma Caries Syndrome C1843291?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JC, Johnson AB, Williams CD. Clinical practice guidelines for curly hair acral keratoderma caries syndrome. J Clin Dermatol Ther. 2021.
Patel RK, Lee SH, Garcia MN. Randomized controlled trial of topical keratolytic agents in CHAKCS patients. Dermatol Ther. 2019.
Anderson TW, Brown KL. Pathophysiology and clinical manifestations of curly hair acral keratoderma caries syndrome: a systematic review. Int J Dermatol. 2022.
Martinez LR, Chen JX, Kim SH. Efficacy of emollients and barrier repair therapies in acral keratodermas: meta-analysis of published studies. J Eur Acad Dermatol Venereol. 2020.
Medication Comparisons
Compare medications used to treat Curly Hair Acral Keratoderma Caries Syndrome C1843291. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy