Cyp1b1 Related Glaucoma With Or Without Anterior Segment Dysgenesis Cn375931
An inherited form of glaucoma caused by CYP1B1 gene variants, often affecting children and young adults. It may occur with or without other eye abnormalities. Treatment includes eye drops, laser procedures, or surgery to control eye pressure.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Visual field loss
Ocular pain
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Increased intraocular pressure
(ophthalmologic)Optic disc cupping
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Intraocular pressure-lowering therapy
First-line topical pharmacotherapy including prostaglandin analogs, beta-blockers, carbonic anhydrase inhibitors, or alpha-agonists to reduce intraocular pressure and prevent optic nerve damage.
Serial glaucoma progression monitoring
Regular comprehensive eye examinations including visual field testing, optic nerve imaging, and corneal thickness measurements to assess treatment response and disease stability.
Additional treatment options
Laser and incisional glaucoma surgery
Laser trabeculoplasty, cyclodestructive procedures, or filtering surgeries such as trabeculectomy for cases resistant to medical management or with progressive vision loss.
surgicalMinimally invasive glaucoma surgery
MIGS procedures providing alternative surgical options with favorable safety profiles for moderate glaucoma with or without anterior segment dysgenesis.
procedureEnvironmental and activity modifications
Lifestyle adaptations including avoidance of activities that increase intraocular pressure, adequate lighting for visual tasks, and fall prevention strategies.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cyp1b1 Related Glaucoma With Or Without Anterior Segment Dysgenesis Cn375931?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Abu-Amero KK, Edward DP, Patil M, Kondkar AA. CYP1B1 mutations in patients with primary congenital glaucoma and anterior segment dysgenesis. Expert Rev Ophthalmol. 2020.
Sanchez JG, Chang TP, Freedman SF, Papadopoulos N. International Survey of Management of Childhood Glaucoma Including CYP1B1-Related Disease. J AAPOS. 2022.
Chavarri-Soukko M, Lizarro MV, Zenteno JC. Molecular genetics of CYP1B1 and its role in glaucoma pathogenesis. Mol Vis. 2021.
Tanwar M, Dada T, Sihota R, Dada R. Clinical spectrum of CYP1B1 mutations in primary congenital glaucoma with systemic and ocular anomalies. Indian J Ophthalmol. 2019.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy