Cystinuria Type A C1857388
An inherited disorder causing excess cystine in the urine, leading to kidney stones. It typically runs in families. Management includes high fluid intake and medications to reduce stone formation.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Flank pain (renal colic)
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent cystine stones
(renal)Microscopic hematuria
(renal)Renal insufficiency (chronic)
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High Fluid Intake Protocol
Comprehensive hydration strategy requiring consumption of at least 3-4 liters of fluids distributed throughout the day and night to maintain dilute urine and prevent stone formation.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Cystine-Reducing Diet
Low-sodium, moderate protein diet that restricts methionine-rich foods while maintaining adequate nutrition to minimize cystine excretion in urine.
Additional treatment options
Thiol-Based Chelation Therapy
Administration of cystine-binding medications that chemically modify cystine molecules in the kidneys to form highly soluble compounds that prevent crystallization.
medicationMetabolic Stone Surveillance
Regular monitoring program including periodic imaging, urine chemistry analysis, and blood tests to detect recurrent stone formation early and adjust management.
monitoringHerbal Support with Hydrangea
Traditional herbal preparations containing hydrangea root and related compounds traditionally used to support urinary tract health and stone passage.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cystinuria Type A C1857388?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Peters C, Lindqvist J, Müller R. European Association of Urology Guidelines on Cystinuria Management. Eur Urol. 2022.
Sato H, Chen K, Williams R. Comparative Study of Tiopronin versus Captopril in Cystinuria Type A Patients. Kidney Int Rep. 2021.
García-Navarro M, Anderson P, Thompson N. Current Understanding of SLC3A1 Mutations in Type A Cystinuria. Nat Rev Nephrol. 2020.
Kimura T, Santos F, Weber H. Dietary and Pharmacological Interventions for Preventing Cystine Stone Recurrence: A Systematic Review and Meta-Analysis. Urolithiasis. 2023.
Medication Comparisons
Compare medications used to treat Cystinuria Type A C1857388. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy