Developmental And Epileptic Encephalopathy 5 C3150731
A genetic brain disorder marked by frequent seizures and impaired development starting in early childhood. Care involves anti-seizure medications and therapies to support daily functioning.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Febrile seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Global developmental delay
(neurologic)Axial hypotonia
(neurologic)Dystonia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-seizure medications (ASMs)
Polytherapy approach often required using combinations of ASMs targeting the multiple seizure types seen in DEE5 including infantile spasms and focal seizures.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Atkins Diet Modification
Less restrictive carbohydrate restriction approach that may provide seizure control benefits while being more sustainable long-term for some families.
Additional treatment options
Corpus Callosotomy
Surgical procedure to sever the corpus callosum and prevent spread of generalized seizures between brain hemispheres. Most effective for atonic seizures causing drop attacks.
procedureSeizure Safety and Environmental Modifications
Comprehensive home and school environment adaptations including seizure alert systems, protective padding, and supervision protocols to prevent injury during seizures.
lifestyleMultidisciplinary Developmental Follow-up
Regular assessment by neurology, developmental pediatrics, genetics, and allied health to coordinate care and adjust interventions based on developmental trajectory.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Developmental And Epileptic Encephalopathy 5 C3150731?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy