Developmental And Epileptic Encephalopathy 8 C1845102
A severe genetic neurological disorder causing frequent seizures and developmental delay or regression in early childhood. Treatment focuses on seizure control and supportive care.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Seizures
(neurologic)Feeding difficulties
(gastrointestinal)Gastroesophageal reflux
(gastrointestinal)Dysphagia
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
First-line anti-epileptic therapy
Standard anti-seizure medication regimen initiated upon diagnosis to control seizure activity. Multiple medication trials may be necessary before identifying an effective regimen.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Epilepsy surgery evaluation
Comprehensive pre-surgical assessment to determine candidacy for resective surgery or disconnection procedures in medically refractory cases. Includes video-EEG monitoring and functional mapping.
Additional treatment options
Developmental surveillance
Regular developmental assessments to track cognitive, motor, and language progress. Enables early identification of regression and guides therapeutic interventions.
monitoringEarly intensive physical rehabilitation
Aggressive physical therapy program targeting motor milestone delays and postural control issues. Evidence supports early intervention for optimal functional outcomes.
physical_therapyResponsive neurostimulation
An implantable closed-loop system that detects seizures and delivers targeted electrical stimulation to abort events. Considered for patients who fail medication trials.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Developmental And Epileptic Encephalopathy 8 C1845102?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Developmental And Epileptic Encephalopathy 8 C1845102. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy