Developmental And Epileptic Encephalopathy 92 C4693362
A rare genetic disorder featuring early-onset epilepsy and severe developmental challenges from infancy due to a specific gene change.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Cortical visual impairment
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Seizures
(neurologic)Developmental delay
(neurologic)Spasticity
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
GABAergic Anti-seizure Medications
Medications that enhance GABAergic signaling may be particularly relevant for conditions involving GABA receptor genes. Treatment selection should target GABAergic pathways when possible.
Low Glycemic Index Treatment (LGIT)
Modified dietary therapy allowing more protein and vegetables while maintaining low glycemic targets. Provides alternative seizure control mechanism with improved tolerability compared to stricter protocols.
Additional treatment options
Responsive Neurostimulation (RNS)
Device that detects seizures and delivers targeted electrical stimulation directly to seizure foci. Considered for patients with focal seizure patterns who are not surgical candidates.
procedureAquatic Therapy
Water-based rehabilitation using buoyancy and resistance to improve motor function, balance, and strength. Provides sensory integration benefits in a low-impact environment.
physical_therapyFamily-centered Psychological Support
Comprehensive support addressing caregiver burden, family dynamics, and psychological wellbeing of all family members affected by caring for a child with severe epilepsy.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Developmental And Epileptic Encephalopathy 92 C4693362?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Developmental And Epileptic Encephalopathy 92 C4693362. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy