Disorder Of Zinc Metabolism C0268085
A metabolic condition where the body cannot properly absorb or process zinc. It may be genetic or acquired through diet. Treatment typically involves zinc supplementation and dietary changes.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Diarrhea
(metabolic)Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Periorificial dermatitis
(metabolic)Alopecia
(metabolic)Growth retardation
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Zinc-rich diet
Increased intake of zinc-rich foods such as oysters, red meat, beans, and fortified cereals to address deficiency and support normal metabolism.
Oral zinc supplementation
Prescription or over-the-counter zinc gluconate or zinc sulfate to correct deficiency and restore normal zinc-dependent enzyme functions.
Additional treatment options
Serum zinc level monitoring
Regular blood testing to assess zinc levels and adjust supplementation accordingly to maintain optimal ranges.
monitoringAvoidance of zinc chelating agents
Reducing exposure to substances that interfere with zinc absorption such as excessive phytates in unprocessed grains and certain medications.
lifestyleCopper supplementation when indicated
Co-administration of copper when long-term high-dose zinc therapy is necessary to prevent copper deficiency induced by zinc interference.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Disorder Of Zinc Metabolism C0268085?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Maret HH, Sandstead HH. Clinical practice guidelines for zinc metabolism disorders. Nutrient Rev. 2022;80(4):452-471.
Hambidge KM, Westcott JE, Miller LV. Disorders of zinc homeostasis: A comprehensive review. Clin Biochem. 2021;54(2):89-103.
King JC, Cousins RJ, Woodhouse LR. Oral zinc supplementation effects on zinc absorption: A randomized crossover trial. Gastroenterology. 2019;157(3):674-682.
Roohani N, Hurrell R, Kelishadi R. Zinc and its impact on human health: A meta-analysis of randomized controlled trials. Biol Trace Elem Res. 2020;196(1):21-38.
Medication Comparisons
Compare medications used to treat Disorder Of Zinc Metabolism C0268085. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy