Distal Monosomy 19p13 3 C4749277
A rare chromosomal deletion involving chromosome 19's short arm end, associated with developmental delays, microcephaly, and health issues. Care focuses on managing symptoms.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Cardiac anomalies
Epilepsy
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Global developmental delay
(neurological)Microcephaly
(neurological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Neurodevelopmental Surveillance Program
Regular neurological and developmental assessments to monitor for seizures, developmental delay, and progressive neurological complications associated with 19p13.3 microdeletions.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Motor Development Intervention
Specialized physical therapy program targeting gross motor delays, balance problems, and coordination difficulties common in distal 19p deletions.
Additional treatment options
Cognitive and Behavioral Assessment Services
Comprehensive neuropsychological evaluation and ongoing support services to address learning disabilities, attention deficits, and behavioral concerns.
psychologicalSymptomatic Pharmacological Management
Medication management for associated conditions such as seizures, hyperactivity, or mood disorders when these manifestations are present.
medicationStructured Family Support and Education Program
Family-centered education about the genetic condition, advocacy skills training, and connection to support resources for caregivers.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Distal Monosomy 19p13 3 C4749277?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Distal Monosomy 19p13 3 C4749277. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy