Ehlers Danlos Syndrome Type 3 C0268337
A genetic disorder characterized by joint hypermobility and connective tissue laxity. It can affect multiple body systems and varies in severity. Management focuses on physical therapy, pain control, and preventing secondary issues.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Joint hypermobility
(musculoskeletal)Joint pain or stiffness
(musculoskeletal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Skin hyperextensibility
(musculoskeletal)Chronic joint pain
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Generalized Joint Hypermobility Physical Therapy
Physical therapy for hypermobile EDS focuses on core stabilization, postural training, and graded exercise to improve proprioception and muscle support around hypermobile joints. Programs are customized to prevent overuse injuries while building functional strength.
Activity Modification and Pacing
Learning to pace activities and recognize pain signals helps prevent post-exertional malaise. Modifying movements that cause subluxations and incorporating rest breaks protects joints while maintaining function.
Additional treatment options
Pain Symptom Management
Comprehensive pain management may include topical treatments, oral analgesics, and muscle relaxants for associated myofascial pain. Medications are used as part of a broader multidisciplinary approach.
medicationAutonomic Dysfunction and GI Screening
Regular monitoring for orthostatic intolerance, gastrointestinal dysmotility, and mast cell activation common in hEDS. Screening allows for early intervention with appropriate specialists.
monitoringChronic Condition Psychological Therapy
Psychological support addresses the significant impact of chronic pain, fatigue, and functional limitations on quality of life. Therapy helps with acceptance, coping strategies, and managing the emotional burden of a lifelong condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Ehlers Danlos Syndrome Type 3 C0268337?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Malfait F, Francomano C, Byers P, et al. The 2017 International Consortium on the Ehlers-Danlos Syndromes. Am J Med Genet C Semin Med Genet. 2017;175(1):8-26.
Tinkle B, Castori M, Francomano C, et al. Hypermobile Ehlers-Danlos syndrome (hEDS): A review. Am J Med Genet A. 2017;173(9):2367-2378.
Hammon M, Krichbaum M, Stumpp CU, et al. Clinical and molecular characterization of hypermobile Ehlers-Danlos syndrome. Genes (Basel). 2021;12(7):1061.
Schubart JR, Bascom R, Graham R, et al. Pain and pain-related symptoms in hypermobile Ehlers-Danlos syndrome: A clinical trial. J Pain Res. 2020;13:2459-2469.
Medication Comparisons
Compare medications used to treat Ehlers Danlos Syndrome Type 3 C0268337. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy