Electron Transfer Flavoprotein Ubiquinone Oxidoreductase Defect C4025586
A rare metabolic disorder impairing the body's ability to convert food into energy. Typically causes muscle weakness, developmental delay, and metabolic crises. Treatment involves specialized dietary management and supportive care.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hypoglycemia
Metabolic acidosis
Fatigue or weight changes
(metabolic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Muscle weakness
(musculoskeletal)Cardiomyopathy
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Fatty Acid Oxidation Supportive Diet
High-carbohydrate, moderate-protein, low-fat dietary approach with frequent small meals to provide alternative energy substrates and reduce metabolic stress.
Fasting Avoidance Protocol
Strict avoidance of prolonged fasting with implementation of scheduled feeding intervals and emergency protocols during illness or procedures.
Additional treatment options
Metabolic Stabilization
Use of metabolic supports, L-carnitine supplementation, and riboflavin as appropriate to support mitochondrial function and energy metabolism.
medicationMetabolic and Cardiac Monitoring
Regular monitoring of metabolic parameters, cardiac function, and growth development to detect complications early and adjust management.
monitoringSupportive and Palliative Care
Multidisciplinary supportive care to address symptom burden, nutritional support, and quality of life considerations in collaboration with metabolic specialists.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Electron Transfer Flavoprotein Ubiquinone Oxidoreductase Defect C4025586?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Electron Transfer Flavoprotein Ubiquinone Oxidoreductase Defect C4025586. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy