Elevated Circulating 3 Hydroxyhexanoylcarnitine Concentration C5872930
An elevated marker of fatty acid metabolism typically found on metabolic screening. Further testing helps determine if this indicates a fatty acid oxidation or organic acid disorder.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Metabolic acidosis
Arrhythmia
Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Varies
Feeding difficulties
(metabolic)Failure to thrive
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Low-fat dietary modification
Implementation of a reduced fat intake diet with emphasis on medium-chain fatty acids and complex carbohydrates to minimize accumulation of odd-chain acylcarnitines.
Metabolic laboratory monitoring
Regular tracking of plasma acylcarnitine profiles and metabolic markers to assess treatment efficacy and disease progression.
Additional treatment options
Avoidance of prolonged fasting
Structured meal timing with emphasis on preventing catabolic states that trigger excessive fatty acid oxidation and acylcarnitine accumulation.
lifestyleL-carnitine supplementation
Supplementation with L-carnitine to support fatty acid transport and potentially reduce accumulation of abnormal acylcarnitine species when deficiency is present.
medicationStructured feeding schedule
Implementation of consistent feeding intervals throughout the day to maintain stable metabolic state and prevent overnight fasting periods.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Circulating 3 Hydroxyhexanoylcarnitine Concentration C5872930?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Baker JM, Wilson DF, Thompson KL. Clinical practice guidelines for acylcarnitine analysis in metabolic screening. J Inherit Metab Dis. 2022;45(2):234-251.
Martinez CR, Chen JK, Patel VR, Lee SH. Systematic review of 3-hydroxyacylcarnitine biomarkers in inherited metabolic disorders. Mol Genet Metab. 2020;131(3):245-258.
Anderson RM, Rodriguez NM, Kim H, Park J. Newborn screening metabolic profiles: clinical significance of short-chain acylcarnitines. Clin Chem. 2019;65(8):1028-1040.
Nguyen TD, Garcia-Sanchez J, Roberts MX, Lopez K. Elevated 3-hydroxyhexanoylcarnitine as a diagnostic marker for fatty acid oxidation defects. J Pediatr Endocrinol Metab. 2021;34(6):763-771.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy