Elevated Urinary Catecholamine Level C0241577
Catecholamines are stress hormones made by the adrenal glands. Elevated urine levels may suggest a tumor called pheochromocytoma or extreme stress. Diagnosis requires imaging and additional testing.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hypertension
(cardiovascular)Headache
(neurological)Palpitations
(cardiovascular)Weight loss
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Imaging for tumor identification
CT, MRI, or MIBG scintigraphy to locate potential pheochromocytoma or other catecholamine-secreting tumors causing elevated urinary levels.
Surgical tumor resection
Laparoscopic or open surgical removal of identified catecholamine-secreting tumors. Pre-operative alpha-blockade is typically required.
Additional treatment options
Alpha-adrenergic blockade
Medical management with alpha-blockers to control hypertension and prepare for potential surgery. Manages symptoms of excess catecholamines.
medicationBeta-blocker adjunct therapy
Beta-blockers added after adequate alpha-blockade to control tachycardia and arrhythmias. Never given before alpha-blockade.
medicationBlood pressure and symptom monitoring
Home blood pressure monitoring and symptom diary to track catecholamine excess manifestations including headaches, sweating, and palpitations.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Urinary Catecholamine Level C0241577?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Lenders JWM, Duh QY, Eisenhofer G, et al. Pheochromocytoma and paraganglioma: Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2014.
van der Knoop MM, Eekhoff EMW, FoPP. Diagnostic Accuracy of Plasma Free Metanephrines for Pheochromocytoma: Systematic Review and Meta-Analysis. Endocr Rev. 2020.
Eisenhofer G, Goldstein DS, Kopin IJ, Crout JR. Pheochromocytoma: Critical Review of Diagnostic and Therapeutic Principles. Clin Chem. 2008.
Feldman JM. Urinary Catecholamines and Blood Pressure in Patients with Pheochromocytoma. Hypertension. 1986.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy