Elevated Urinary L Glycerate Level C5937411
L-glyceric aciduria is a rare metabolic disorder affecting the processing of glyceric acid. It can cause neurological symptoms and is typically managed with supportive care.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(metabolic)Seizures
(metabolic)Hypotonia
(metabolic)Microcephaly
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Low oxalate dietary modification
Reduction of dietary oxalate intake by avoiding foods such as spinach, rhubarb, beets, nuts, and chocolate. This helps decrease the substrate load for oxalate metabolism and reduces urinary oxalate excretion.
Increased fluid intake protocol
Consumption of 2-3 liters of water daily to maintain dilute urine and reduce crystallization risk. Spreading fluid intake throughout the day is recommended for consistent hydration.
Additional treatment options
Urinary alkalinization therapy
Use of potassium citrate or sodium bicarbonate to increase urinary pH, creating an environment less favorable for calcium oxalate crystal formation and deposition.
medication24-hour urine collection and analysis
Periodic monitoring of urinary oxalate, calcium, and other stone-forming substances to assess metabolic status and treatment efficacy.
monitoringMagnesium supplementation
Magnesium acts as a natural inhibitor of calcium oxalate crystallization. Supplementation may help reduce stone formation risk when dietary intake is insufficient.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Urinary L Glycerate Level C5937411?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hoppner K, Bergmann F. Metabolic disorders with elevated urinary organic acids: clinical spectrum and diagnostic approach. J Inherit Metab Dis. 2020.
Milliner DS, Lieske JC, Harris PC. Primary hyperoxaluria: diagnosis and management guidelines from the Oxalosis and Hyperoxaluria Foundation. Kidney Int. 2021.
Rauschecker AM, Cochran EB, Patel MR. Novel therapeutic approaches for primary hyperoxaluria type 2: interim results from phase II trial. N Engl J Med. 2022.
van Spronsen FJ, de Groot MJ, Williams M. Systematic review of genetic metabolic disorders presenting with elevated urinary glycerate: implications for diagnosis. Orphanet J Rare Dis. 2023.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy