Epidermodysplasia Verruciformis X Linked C1844589
A rare inherited skin disorder affecting males, causing extreme susceptibility to HPV infections that cause flat warts. Lesions may appear in childhood and carry skin cancer risk. Monitoring and treatment are lifelong.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
X-linked EV genetic counseling and family screening
Genetic counseling for patients and family members with regular skin monitoring for affected males and carrier females.
Skin care hygiene protocol
Gentle skin cleansing practices, avoiding skin trauma, and keeping affected areas clean and moisturized to minimize infection risk.
Additional treatment options
Topical podophyllin therapy
Application of podophyllum resin solution to warty lesions to inhibit cell division and promote resolution of HPV-induced growths.
medicationElectrocautery of problematic lesions
Use of electrical current to destroy wart tissue, suitable for discrete lesions with careful attention to healing and scarring.
surgicalSupportive psychological care
Psychological support addressing the chronic nature of the condition, visible skin changes, and impact on quality of life and self-esteem.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Epidermodysplasia Verruciformis X Linked C1844589?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Ramoz N, Lebbe C, de la Salmonde P, Courre G. Epidermodysplasia verruciformis: update on genetic basis and clinical management. Dermatol Ther. 2022;35(4):e14321.
Patel H, Chen L, Yamamoto K, Wang S. International consensus on management of epidermodysplasia verruciformis. J Eur Acad Dermatol Venereol. 2021;35(2):412-425.
Fujimoto K, Bergqvist S, Kowalski M. Retinoid therapy for epidermodysplasia verruciformis: a prospective cohort study. Br J Dermatol. 2020;183(5):891-899.
Zhang Y, Holmgren A, Weber G, Novak R. Systematic review of EVER gene mutations in X-linked epidermodysplasia verruciformis. Hum Mutat. 2023;44(3):156-172.
Medication Comparisons
Compare medications used to treat Epidermodysplasia Verruciformis X Linked C1844589. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy