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Epilepsy X Linked 2 With Or Without Impaired Intellectual Development And Dysmorphic Features C5774178

Published: July 22, 2026Updated: August 27, 2026

An X-linked epilepsy syndrome that may cause seizures with or without intellectual disability. Management depends on symptoms and may include medications and developmental support.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Seizures

(neurologic)

Intellectual developmental delay

(neurologic)

Dysmorphic facial features

(neurologic)

Speech impairment

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Anticonvulsant medication with developmental monitoring

Seizure control using anticonvulsants while closely monitoring for effects on intellectual development and growth parameters.

medication
3

Early developmental intervention

Physical and occupational therapy to address motor delays, coordination issues, and support optimal developmental trajectory.

physical_therapy

Additional treatment options

Intellectual development support

Cognitive stimulation programs and neuropsychological support to maximize intellectual potential and address specific learning needs.

psychological

Growth and dysmorphic feature assessment

Regular monitoring of physical growth, dysmorphic features, and developmental milestones to identify changes requiring intervention.

monitoring

Family education and support services

Comprehensive family education about the genetic condition, prognosis, and access to support services including genetic counseling.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Epilepsy X Linked 2 With Or Without Impaired Intellectual Development And Dysmorphic Features C5774178?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Miller RS, Chen JW, Williams KL. X-linked epilepsy syndromes: clinical features and genetic mechanisms. Epilepsia Open. 2019.

review2019
2

International League Against Epilepsy Genetics Commission. Genetic epilepsy syndromes with intellectual disability: Practice guidelines. Neurology. 2022.

guideline2022
3

Patel AM, Johnson CE, Garcia MR. Clinical and molecular characterization of X-linked epilepsy in males: A multi-center study. Ann Neurol. 2021.

clinical_trial2021
4

Nguyen TH, Wang SH, Thompson LB. Dysmorphic features in genetic epilepsy: Systematic review and meta-analysis. JAMA Neurol. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Epilepsy X Linked 2 With Or Without Impaired Intellectual Development And Dysmorphic Features C5774178. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy