Erythrocytosis Familial 4 C2673187
A genetic disorder leading to elevated red blood cell counts. This makes blood thicker and can affect circulation. Regular monitoring and phlebotomy help manage blood viscosity.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Headache
(hematologic)Fatigue
(hematologic)Aquagenic pruritus
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Therapeutic Phlebotomy
Regular phlebotomy sessions to maintain hematocrit within target ranges, reducing the risk of hyperviscosity symptoms such as headache, dizziness, and thrombosis.
Erythropoietin Level Monitoring
Regular assessment of EPO levels to differentiate familial forms and monitor disease progression, guiding treatment decisions.
Additional treatment options
Cytoreductive Therapy Consideration
In refractory cases, medications that suppress bone marrow production of red blood cells may be considered to control erythropoiesis.
medicationSmoking Cessation
Complete avoidance of tobacco products as smoking increases carboxyhemoglobin, further reducing oxygen delivery and exacerbating compensatory erythrocytosis.
lifestyleAntioxidant-Rich Diet
Consuming foods high in antioxidants to support vascular health and counteract oxidative stress associated with elevated red blood cell counts.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Erythrocytosis Familial 4 C2673187?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
McMullin MF, Harrison CN, Ali S, et al. A guideline for the diagnosis, management, and surveillance of clonal and non-clonal erythrocytosis. Br J Haematol. 2023.
Lee FS, Percy MJ. The HIF pathway and erythrocytosis. Annu Rev Pathol. 2021.
Bento C, Almeida H, Ribeiro ML. Genetic characterization of familial erythrocytosis in a Portuguese cohort. Haematologica. 2020.
Kralovics R. Molecular genetics of erythrocytosis. In: Haematology: Basic Principles and Practice. 7th ed. Elsevier; 2022.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy