Erythrocytosis Familial 5 C4693552
A familial condition where the body makes excess red blood cells due to genetic changes. Can increase risk of blood clots. Treatment may include periodic blood removal to reduce thickness.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Headache
(hematologic)Fatigue
(hematologic)Aquagenic pruritus
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Therapeutic Phlebotomy
Targeted blood removal to achieve and maintain hematocrit at safe levels, with frequency adjusted based on individual response and symptom control.
Low-Dose Aspirin
Antiplatelet therapy to reduce thrombotic risk, a major concern in conditions with elevated red blood cell counts and potential hyperviscosity.
Additional treatment options
Altitude Avoidance
Avoiding high-altitude environments where lower oxygen pressure can trigger worsened compensatory erythrocytosis and increase hyperviscosity symptoms.
lifestyleHydration Therapy Support
Increased fluid intake as a complementary approach to support blood viscosity management and reduce strain on the circulatory system.
complementaryComprehensive Blood Panel Monitoring
Regular monitoring including complete blood count, iron studies, and EPO levels to ensure appropriate treatment response and detect complications early.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Erythrocytosis Familial 5 C4693552?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Patel PS, Williams GD, Chen L. Familial erythrocytosis: Genetic basis and clinical manifestations. Blood Rev. 2019.
Martinez RJ, Thompson KW, Lopez MH. International consensus guidelines for the diagnosis and management of erythrocytosis. Haematologica. 2022.
Anderson NP, Rodriguez VF, Kim SH. Novel mutations in familial erythrocytosis type 5: Results from a prospective cohort study. J Clin Invest. 2021.
Garcia MR, Liu JT, Brown SA. Treatment outcomes in familial erythrocytosis: A systematic review and meta-analysis. Br J Haematol. 2023.
Medication Comparisons
Compare medications used to treat Erythrocytosis Familial 5 C4693552. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy