Exudative Vitreoretinopathy 4 Digenic C4016840
Caused by mutations in two different genes, this form can cause retinal vessel abnormalities. Careful monitoring and treatment are important.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Sudden vision loss
Photopsia
Vitreous hemorrhage
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Floaters
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-VEGF intravitreal therapy
Vascular endothelial growth factor inhibitor injections targeting abnormal vessel formation characteristic of digenic exudative vitreoretinopathy.
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Peripheral laser barricade
Strategic laser application to peripheral retina to create barriers against progression of exudation and new vessel formation.
Additional treatment options
Scleral buckle procedure
Placement of silicone band around the globe to support detached retina and reduce traction in cases with rhegmatogenous components.
surgicalMultimodal imaging protocol
Systematic monitoring using OCT, widefield angiography, and electroretinography to assess disease activity and treatment outcomes.
monitoringLow-impact activity modification
Guidance on avoiding activities that increase intraocular pressure or retinal stress, such as heavy lifting or contact sports.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Exudative Vitreoretinopathy 4 Digenic C4016840?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy