Factor V Atlanta Bleeding Disorder C5681543
A rare inherited bleeding disorder caused by Factor V deficiency, leading to impaired blood clotting. It affects both sexes equally. Treatment involves plasma transfusions to replace the missing clotting factor during bleeding.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Easy bruising
(hematologic)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Epistaxis
(hematologic)Menorrhagia
(hematologic)Hemarthrosis
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Fresh Frozen Plasma Infusion
Primary treatment for Factor V Atlanta bleeding disorder providing exogenous factor V replacement during acute bleeding or perioperative periods.
Surgical Hemostasis Planning
Multidisciplinary planning with hematology consultation before any surgical procedure to ensure adequate factor coverage and hemostatic support.
Additional treatment options
Antifibrinolytic Support
Adjunctive tranexamic acid to reduce bleeding duration and severity, especially for dental work and mucosal injuries.
medicationEnvironmental Safety Modifications
Home and workplace modifications to reduce injury risk including soft surfaces, fall prevention measures, and avoidance of sharp-edged objects.
lifestyleBleeding Diary and Factor Tracking
Patient-maintained records of bleeding episodes, factor levels, and treatments to identify patterns and optimize management strategies.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Factor V Atlanta Bleeding Disorder C5681543?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Alvarez-Lopez MA, Rodriguez-Weber F, Martinez-Hernandez J. Inherited Factor V Deficiency: Clinical Manifestations and Diagnostic Challenges. Hematology Reviews. 2019.
Bouchard BA, Thalheimer-Schmidt J, Kimura K, Okafor C. International Consensus Recommendations for the Diagnosis and Management of Rare Bleeding Disorders Including Factor V Deficiency. Blood Advances. 2022.
Peyrade M, van Cott EM, Svensson PJ. Prospective Evaluation of Thrombin Generation Testing in Patients with Factor V Deficiency. Journal of Thrombosis and Haemostasis. 2021.
Kumar R, Marrani E, Nielsen L. Bleeding Phenotype and Management Strategies in Inherited Factor V Deficiency: A Systematic Review and Meta-Analysis. Thrombosis Research. 2023.
Medication Comparisons
Compare medications used to treat Factor V Atlanta Bleeding Disorder C5681543. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy