Factor Xiii A Subunit Deficiency Of C2750514
Factor XIII A subunit deficiency is a rare inherited bleeding disorder where blood clots fail to stabilize properly. It can cause prolonged bleeding after injury, surgery, or spontaneous bleeding episodes. Treatment with factor XIII replacement therapy helps prevent bleeding complications.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intracranial hemorrhage
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Poor wound healing
(hematologic)Umbilical stump bleeding
(hematologic)Post-traumatic bleeding
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cryoprecipitate Transfusion
Cryoprecipitate contains Factor XIII and fibrinogen, used for acute bleeding or as prophylaxis before surgical procedures.
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Factor XIII Concentrate
Purified Factor XIII concentrate provides targeted replacement with lower infection risk compared to plasma products.
Additional treatment options
Factor XIII Level Testing
Regular monitoring of Factor XIII levels helps guide prophylaxis schedules and prevent breakthrough bleeding episodes.
monitoringAvoidance of Trauma-prone Activities
Patients should avoid activities with high injury risk since Factor XIII deficiency causes delayed bleeding complications.
lifestylePatient Education and Emergency Planning
Comprehensive education on bleeding recognition, emergency care protocols, and medical alert identification improves outcomes.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Factor Xiii A Subunit Deficiency Of C2750514?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Factor Xiii A Subunit Deficiency Of C2750514. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy