Factor Xiii B Subunit Deficiency Of C2750481
Factor XIII B subunit deficiency is a rare genetic bleeding disorder affecting both males and females. The condition impairs proper blood clot formation and stability. Management typically involves plasma transfusions or specific factor concentrates to prevent bleeding.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Spontaneous intracranial bleeding
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Poor wound healing
(hematologic)Umbilical stump bleeding
(hematologic)Post-surgical bleeding complications
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cryoprecipitate Transfusion
Primary treatment for Factor XIII B subunit deficiency involves cryoprecipitate to replace functional Factor XIII activity.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Recombinant Factor XIII Concentrate
When available, recombinant Factor XIII provides consistent dosing with minimal infectious risk for prophylaxis.
Additional treatment options
Prophylactic Infusion Schedule Assessment
Regular review of bleeding history and Factor XIII levels helps optimize prophylactic dosing intervals for each patient.
monitoringSurgical Hemostasis Planning
Preoperative hematology consultation ensures adequate Factor XIII replacement coverage for all surgical procedures.
surgicalMedical Alert Identification
Wearing medical alert jewelry ensures proper identification during emergencies when delayed bleeding may be misinterpreted.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Factor Xiii B Subunit Deficiency Of C2750481?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Factor Xiii B Subunit Deficiency Of C2750481. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy