Familial Adenomatous Polyposis 1 C2713442
Familial adenomatous polyposis 1 is an inherited condition causing numerous polyps to form in the colon, significantly increasing colorectal cancer risk. It follows an autosomal dominant inheritance pattern. Surveillance and preventive surgery are key management strategies.
Key facts at a glance
- ICD-10
- D13.91
- ICD-11
- 3A00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Colorectal polyps
(gastrointestinal)Change in bowel habits
(gastrointestinal)Abdominal pain
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Prophylactic colectomy
Surgical removal of the colon as primary cancer prevention, typically recommended when polyp burden becomes unmanageable or high-grade dysplasia is detected. Various surgical approaches available depending on individual factors.
Regular endoscopic surveillance
Frequent colonoscopic monitoring to track polyp development and identify transformation to dysplasia or carcinoma. Upper GI endoscopy also indicated for duodenal polyp surveillance.
Additional treatment options
Chemopreventive therapy
Pharmacological agents such as NSAIDs or COX-2 inhibitors may be used to reduce polyp burden and slow disease progression as adjunct to surveillance and surgical planning.
medicationRisk-reducing lifestyle modifications
Adoption of healthy lifestyle habits including regular physical activity, avoidance of smoking, limiting red meat and processed foods, and maintaining healthy weight may provide additional cancer risk reduction.
lifestyleGenetic counseling and decision support
Comprehensive genetic counseling for patients and at-risk family members, including discussion of reproductive options, psychological preparation for prophylactic surgery, and ongoing support for living with hereditary cancer risk.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Familial Adenomatous Polyposis 1 C2713442?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy