Fanconi Anemia Complementation Group D2 C3160738
A genetic disorder involving defective DNA repair that leads to bone marrow failure, anemia, and heightened cancer risk. Treatment focuses on transfusions, monitoring, and bone marrow transplant when needed.
Key facts at a glance
- ICD-10
- D61.03
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pancytopenia
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Fatigue
(hematologic)Short stature
(hematologic)Renal malformation
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Hematopoietic Stem Cell Transplantation (HSCT)
Definitive treatment for bone marrow failure using allogeneic stem cells from matched sibling or unrelated donors. Success rates vary by donor source and patient age.
Granulocyte Colony-Stimulating Factor (G-CSF)
Growth factor therapy to stimulate neutrophil production and reduce infection risk in patients with neutropenia. Often used as supportive care or bridge to transplant.
Additional treatment options
Bone Marrow Failure Monitoring
Serial bone marrow aspirates and biopsies to assess disease progression, cellularity, and cytogenetic changes that may indicate transformation to MDS or leukemia.
monitoringRehabilitation for Skeletal Abnormalities
Specialized physical therapy programs addressing limb malformations, joint contractures, and mobility limitations common in Fanconi anemia to maintain function.
physical_therapyPsychosocial Support Services
Comprehensive psychological support including counseling, support groups, and family therapy to address chronic illness burden, anxiety, and depression common in FA patients.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Fanconi Anemia Complementation Group D2 C3160738?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Fanconi Anemia Complementation Group D2 C3160738. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy