Female External Genitalia In Individual With 46 Xy Karyotype C1848178
A condition where an individual with a male karyotype has external genitalia that appear typically female. It results from differences in sexual development and may involve hormonal and surgical considerations.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Primary amenorrhea
(reproductive)Breast development (female)
(reproductive)Lack of pubic hair
(reproductive)Inguinal hernia
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Psychological counseling and support
Comprehensive psychological support for the individual and family addressing gender identity, intersex experiences, and decision-making regarding treatment options. Mental health professional involvement is essential throughout the process.
Gonadal malignancy surveillance
Regular monitoring for gonadoblastoma and malignancy risk in dysgenetic gonads. Includes imaging and tumor marker assessment according to clinical guidelines and individual risk factors.
When to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Female External Genitalia In Individual With 46 Xy Karyotype C1848178?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Lee PA, Houk CP, Ahmed SF, Hughes IA. Consensus statement on management of intersex disorders. Pediatrics. 2006;118(2):488-500.
Ahmed SF, Achermann JC, Arlt W, Balen AH, Conway G, Edwards ZL, et al. UK guidance on clinical management for disorders of sex development. Sex Dev. 2011;5(4):159-176.
Bertelloni S, Dati E, Baroncelli GI. Disorders of sex development: hormonal management in childhood. Ital J Pediatr. 2018;44(Suppl 2):141.
Gaudino R,_PROTECT_INTEGRITY, Tarani L. 46,XY differences of sex development: an overview of genetic and clinical aspects. J Endocrinol Invest. 2020;43(8):1029-1041.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy