Focal Segmental Glomerulosclerosis 9 C4015555
A kidney disorder where scar tissue develops in parts of the glomeruli, causing protein loss and potentially kidney failure. Treatment aims to reduce proteinuria and slow progression.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Sudden severe flank pain
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Frothy urine
(renal)Peripheral edema
(renal)Fatigue
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corticosteroid-based remission induction
Intensive corticosteroid therapy aims to induce remission in newly diagnosed FSGS by suppressing the inflammatory and immune processes damaging podocytes.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
RAAS blockade with ACE inhibitors or ARBs
These agents provide essential kidney protection by reducing proteinuria and blood pressure, slowing the progression of glomerulosclerosis.
Additional treatment options
Mycophenolate mofetil
For cases resistant to initial corticosteroid therapy, mycophenolate mofetil offers an alternative immunosuppressive approach with a different mechanism of action.
medicationSmoking cessation and alcohol moderation
Eliminating tobacco use and limiting alcohol consumption reduces cardiovascular risk and may help preserve renal function in FSGS patients.
lifestyleOmega-3 fatty acid supplementation
Some evidence suggests omega-3 supplementation may have modest anti-inflammatory effects and potentially slow disease progression in glomerular diseases.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Focal Segmental Glomerulosclerosis 9 C4015555?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy