Fragile X Associated Tremor Ataxia Syndrome C1839780
A neurological condition affecting older adults with a Fragile X gene premutation, causing tremor, balance problems, and cognitive changes. Management involves symptom relief and supportive therapies.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Progressive gait ataxia
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intention tremor
(neurologic)Peripheral neuropathy
(neurologic)Cognitive impairment
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Tremor and Movement Symptom Control
Pharmacological management of tremor and ataxia symptoms using medications that modulate neurotransmitter function. Treatment is individualized based on symptom severity and tolerability.
Balance and Gait Rehabilitation
Specialized physical therapy program focused on improving balance, reducing fall risk, and maintaining mobility. Includes gait training, strengthening exercises, and balance activities.
Additional treatment options
Progressive Disease Monitoring
Regular neurological assessments to monitor disease progression, assess medication efficacy, and identify emerging symptoms such as cognitive decline or autonomic dysfunction.
monitoringNeuropsychological Support Services
Cognitive assessment and intervention for executive function deficits, memory problems, and emotional changes associated with FXTAS. Includes coping strategies and family education.
psychologicalFall Prevention and Safety Modifications
Home safety assessment and modifications including grab bars, shower chairs, and mobility aids. Education on fall prevention strategies and energy conservation techniques.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Fragile X Associated Tremor Ataxia Syndrome C1839780?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Fragile X Associated Tremor Ataxia Syndrome C1839780. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy