Fragile X Syndrome C0016667
A genetic condition causing intellectual disability and developmental delays, primarily affecting males. Management includes supportive therapies, educational support, and addressing specific symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Speech and language delay
(neurologic)Hyperextensible joints
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and Educational Interventions
Early intervention programs using applied behavior analysis and structured educational approaches help address developmental delays, communication challenges, and behavioral issues associated with Fragile X Syndrome.
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Speech and Language Therapy
Individualized speech therapy addressing apraxia, language comprehension, and social communication deficits common in Fragile X patients to improve functional communication skills.
Additional treatment options
Symptom Management Medications
Pharmacological management of co-occurring conditions such as anxiety, attention deficits, mood instability, and seizures when present, using appropriately selected agents.
medicationOccupational Therapy
Sensory integration therapy and fine motor skill development to address hypersensitivity, motor coordination difficulties, and daily living skill development.
physical_therapyFamily Support and Environmental Modifications
Structured home environment with predictable routines, sensory-friendly spaces, and family education programs to reduce anxiety and improve daily functioning.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Fragile X Syndrome C0016667?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hagerman RJ, Berry-Kravis E, Kaufmann WE, et al. Consensus guidelines for fragile X syndrome. Dev Med Child Neurol. 2022;64(5):589-601.
McDuffie A, Thurman AJ, Hagerman RJ, Abbeduto L. Neurodevelopmental disorders: fragile X syndrome. Nat Rev Dis Primers. 2020;6(1):45.
Berry-Kravis EM, Lindemann L, Jonch AE, et al. Arbaclofen in fragile X syndrome: results of phase 3 trials. Transl Psychiatry. 2019;9(1):114.
Sansone SM, Widaman KF, Hall SS, et al. Psychopharmacological targets in fragile X syndrome: a systematic review. J Neurodev Disord. 2018;10(1):25.
Medication Comparisons
Compare medications used to treat Fragile X Syndrome C0016667. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy