Fraser Syndrome 3 C4540040
Another genetic variant of Fraser syndrome with comparable multi-system involvement including eye, ear, kidney, and genital abnormalities. Care focuses on managing specific health issues.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Cryptophthalmos
Anal atresia
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Syndactyly
(musculoskeletal)Ear malformations (microtia)
(ear)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Genitourinary reconstruction
Corrective surgery for renal and genitourinary tract abnormalities to preserve function and prevent complications.
Ophthalmologic reconstruction
Surgical management of cryptophthalmos with reconstructive procedures to protect cornea and improve cosmetic appearance.
Additional treatment options
Renal function monitoring
Regular assessment of kidney function through serum creatinine, urinalysis, and imaging to detect and manage hydronephrosis.
monitoringHand function therapy
Specialized therapy following syndactyly release to optimize finger dexterity, strength, and functional use of hands.
physical_therapyFamily counseling program
Comprehensive psychological support addressing body image concerns, medical trauma, and family adjustment to chronic condition management.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Fraser Syndrome 3 C4540040?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Fraser Syndrome 3 C4540040. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy