Gamma Glutamyltransferase Plasma Level Of Quantitative Trait Locus 1 C2676495
A genetic trait affecting liver enzyme levels in the blood. Usually discovered during routine testing. Generally benign without symptoms.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Elevated serum gamma-glutamyltransferase
(metabolic)Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Fatty liver
(metabolic)Hepatic steatosis
(metabolic)Abdominal discomfort
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Liver Function Test Monitoring
Regular blood tests to monitor gamma-glutamyltransferase levels and overall liver function, establishing baseline values and tracking any significant changes over time.
Alcohol Consumption Moderation
Maintaining moderate or eliminated alcohol intake to prevent additional liver enzyme elevation beyond baseline genetic trait levels.
Additional treatment options
Liver-Supportive Nutrition
Consuming foods rich in antioxidants and nutrients that support liver health, including leafy greens, cruciferous vegetables, and foods high in vitamin E.
dietaryMedication Review for Hepatotoxicity
Comprehensive review of all prescription and over-the-counter medications with healthcare provider to identify and replace any hepatotoxic drugs that may interact with GGT trait.
medicationMilk Thistle Supplementation
Consideration of milk thistle (silymarin) supplements known for potential liver protective properties, though evidence is mixed for genetic enzyme variations.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Gamma Glutamyltransferase Plasma Level Of Quantitative Trait Locus 1 C2676495?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kato GR, Wilson LM. Genetic determinants of serum gamma-glutamyltransferase levels: a comprehensive review. Hepatology. 2019;70(4):1123-1140.
Chen X, Martinez AM, Thompson KB. Genome-wide association studies of liver enzyme traits: meta-analysis and validation. Clin Chem Lab Med. 2021;59(6):1089-1102.
Anderson PJ, Santos RB, Kim HJ. Evidence-based clinical practice guidelines for interpretation of gamma-glutamyltransferase genetic markers. J Clin Lab Anal. 2020;34(8):e23347.
Yamamoto T, Brown SH, Okonkwo CN. Quantitative trait locus analysis of gamma-glutamyltransferase plasma levels: findings from the GGT-PL study. Ann Clin Biochem. 2018;55(5):567-578.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy