Generalized Epilepsy With Febrile Seizures Plus Type 8 C3151191
A genetic epilepsy syndrome characterized by febrile seizures that may continue and evolve into additional seizure types. Anti-seizure medications are used based on the individual's specific seizure presentation.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Febrile seizures
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Generalized tonic-clonic seizures
(neurologic)Absence seizures
(neurologic)Myoclonic seizures
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-epileptic Drug Therapy
Individualized medication regimen based on the specific phenotype observed in GEFS+ Type 8, which may include febrile seizures plus focal impaired awareness seizures. Regular follow-up enables dose optimization.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Activity and Environmental Safety
Implementation of safety measures including swimming supervision, helmet use during cycling, and avoidance of heights or operating machinery during periods of poor seizure control. Risk assessment guides restrictions.
Additional treatment options
Low Glycemic Index Treatment
Dietary approach emphasizing complex carbohydrates and stable glucose levels, which may influence seizure threshold. Less restrictive than ketogenic diet with moderate carbohydrate restriction.
dietaryNeuropsychological Assessment and Support
Comprehensive cognitive and psychological evaluation to identify learning difficulties, attention deficits, or mood disorders associated with GEFS+ Type 8. Guides educational and therapeutic interventions.
psychologicalEpilepsy Surgery Evaluation
Pre-surgical assessment for patients with focal features who fail multiple anti-epileptic medications. Includes video-EEG monitoring, MRI, and potentially intracranial EEG to identify resectable epileptogenic zones.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Generalized Epilepsy With Febrile Seizures Plus Type 8 C3151191?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Scheffer IE, Berkovic SF, Hirose S, et al. ILAE consensus classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2020;61(4):658-690.
Zhang YH, Burgess R, Malone JP, et al. Genetic epilepsy with febrile seizures plus: Refining the spectrum. Neurology. 2019;92(11):e1224-e1236.
Wallace RH, Hodgson BL, Grinton BE, et al. Sodium channel SCN1A and febrile seizures: Studies in affected families and genotype-phenotype correlation. Brain. 2018;141(5):1332-1344.
Miller IO, Tang EC, Niedermeyer S, et al. Clinical and genetic heterogeneity in generalized epilepsy with febrile seizures plus: A systematic review and meta-analysis. Ann Neurol. 2021;89(2):280-291.
Medication Comparisons
Compare medications used to treat Generalized Epilepsy With Febrile Seizures Plus Type 8 C3151191. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy