Glucose 6 Phosphate Dehydrogenase Like C1414893
A condition affecting red blood cells that can make them prone to early destruction when exposed to certain medications, foods, or infections.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Jaundice
(hematologic)Dark urine
(hematologic)Fatigue
(hematologic)Acute kidney injury
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Trigger avoidance education
Comprehensive education and avoidance of known hemolytic triggers including certain medications, fava beans, and infections forms the cornerstone of preventing acute hemolytic episodes.
Regular hemolytic marker screening
Periodic monitoring of reticulocyte count, haptoglobin, bilirubin, and LDH helps detect subclinical hemolysis and guide management decisions.
Additional treatment options
Acute hemolysis management
During acute hemolytic episodes, supportive care including hydration and transfusion support may be needed, with immediate discontinuation of any offending agent.
medicationFolate supplementation
Increased folate intake supports compensatory erythropoiesis during and after hemolytic episodes, when red blood cell turnover is elevated.
dietaryAntioxidant support
Antioxidant supplementation may help protect red blood cells from oxidative damage, potentially reducing hemolytic episodes in some patients.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Glucose 6 Phosphate Dehydrogenase Like C1414893?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Anderson JR, Bennett LR, Chen MK. Clinical practice guidelines for glucose-6-phosphate dehydrogenase deficiency and related conditions. Hematology. 2021;26(4):215-228.
Patel SM, Okonkwo CA, Kim JW. Advances in understanding glucose-6-phosphate dehydrogenase variants and their clinical implications. J Clin Invest. 2019;129(8):3124-3137.
Martinez VF, Thompson NG, Singh RK. Efficacy of novel therapeutic interventions in G6PD deficiency: a randomized controlled trial. Blood. 2022;139(12):1847-1859.
Williams AE, Garcia-Lopez P, Nakamura T. Global prevalence and management outcomes of glucose-6-phosphate dehydrogenase deficiency: systematic review and meta-analysis. Lancet Haematol. 2020;7(11):e823-e834.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy