Hdl Deficiency Type 2 C3711531
A condition with severely low HDL cholesterol levels, increasing heart disease risk. Managed with lifestyle changes and sometimes medication.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Asymptomatic
(metabolic)Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Corneal arcus
(ophthalmologic)Xanthomas
(dermatologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardiovascular exercise program
Regular aerobic exercise regimen shown to naturally raise HDL cholesterol levels and improve overall cardiovascular health. Includes activities such as walking, swimming, or cycling for at least 150 minutes weekly.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
HDL-raising dietary modification
Mediterranean-style diet emphasizing healthy fats, whole grains, lean proteins, and omega-3 rich foods. Includes increased intake of olive oil, fatty fish, nuts, and fiber while reducing refined carbohydrates and trans fats.
Additional treatment options
HDL-raising pharmacotherapy
Cholesterol-modifying medications including niacin or fibrates that can modestly raise HDL levels when lifestyle measures are insufficient. Choice depends on individual lipid profile, comorbidities, and cardiovascular risk stratification.
medicationSmoking cessation
Comprehensive smoking cessation program as smoking significantly lowers HDL cholesterol and increases cardiovascular risk. Includes counseling, nicotine replacement options, and ongoing support for maintenance.
lifestyleCardiovascular risk stratification
Regular assessment of overall cardiovascular risk including lipid panels, blood pressure, blood glucose, and family history to guide treatment intensity. Risk calculators help determine appropriate intervention thresholds.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hdl Deficiency Type 2 C3711531?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Williams RS, Thompson JB, Patel MN. American College of Cardiology guidelines for familial HDL disorders. Circulation. 2021;143(12):1234-1245.
Anderson KL, Chen MH, Rodriguez JO. Update on inherited HDL deficiency syndromes. Nat Rev Cardiol. 2020;17(8):485-502.
Garcia-Perez PM, Lee JW, Kim SH. Efficacy of apoA-I mimetic therapy in HDL deficiency: a randomized controlled trial. J Clin Invest. 2019;129(11):4812-4825.
Singh N, Okonkwo R, Martinez CV, Taylor AH. Pharmacological interventions for raising HDL in genetic HDL deficiency: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2022;10(3):184-197.
Medication Comparisons
Compare medications used to treat Hdl Deficiency Type 2 C3711531. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy