Hemophilia A With Vascular Abnormality C1844137
A bleeding disorder combining factor VIII deficiency with blood vessel abnormalities. It mainly affects males due to X-linked inheritance. Treatment involves factor replacement therapy and careful management of bleeding episodes.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intracranial hemorrhage
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Joint hemorrhage (hemarthrosis)
(hematologic)Spontaneous bruising
(hematologic)Muscle hematoma
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Factor VIII Replacement Therapy
Intravenous administration of recombinant or plasma-derived factor VIII concentrate to replace deficient clotting factor and prevent or treat bleeding episodes in hemophilia A.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Desmopressin Acetate
Synthetic hormone that stimulates release of endogenous factor VIII and von Willebrand factor from endothelial stores, useful for mild hemophilia A.
Additional treatment options
Bleeding Precaution Protocol
Avoidance of activities with high injury risk, NSAIDs, anticoagulants, and blood-thinning medications. Use of protective gear and soft-bristled toothbrushes.
lifestyleJoint Protection and Rehabilitation
Physical therapy program emphasizing range of motion exercises, muscle strengthening, and joint protection techniques to prevent hemarthrosis and manage existing arthropathy.
physical_therapyInhibitor Screening and Management
Regular testing for factor VIII inhibitor development with Bethesda assay; immune tolerance induction protocols for patients who develop inhibitors.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hemophilia A With Vascular Abnormality C1844137?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Hemophilia A With Vascular Abnormality C1844137. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy