Hepatitis E Virus Infection C0085293
A liver infection caused by the Hepatitis E virus, typically spread through contaminated water. Most people recover fully with rest and supportive care, though it can be serious in pregnant women and those with weakened immune systems.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hepatobiliary)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Jaundice
(hepatobiliary)Fatigue
(hepatobiliary)Nausea
(hepatobiliary)Pruritus
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Supportive Care and Clinical Observation
Hepatitis E in immunocompetent individuals is typically self-limiting, requiring supportive care with monitoring of symptoms and liver function. Most patients recover spontaneously within 4-6 weeks without antiviral therapy.
Rest and Adequate Hydration
Sufficient rest to support immune function and recovery, combined with adequate hydration to support liver function and overall recovery. Strenuous activities and exercise should be avoided during the acute phase.
Additional treatment options
Nutritional Support During Recovery
Light, easily digestible meals focusing on adequate calories and nutrients to support recovery. Small frequent meals may help with nausea. Avoid fatty foods, alcohol, and medications metabolized by the liver during acute infection.
dietaryAntiviral Therapy for Severe or Persistent Cases
Ribavirin or sofosbuvir-based regimens may be considered for immunocompromised patients or those with severe hepatitis E infection who fail to clear the virus spontaneously. Treatment decisions should be made by infectious disease or hepatology specialists.
medicationHospitalization for Severe Hepatitis
In cases of fulminant hepatic failure or severe cholestasis, hospitalization may be required for intensive monitoring, supportive care, and potential consideration for liver transplantation in life-threatening cases.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hepatitis E Virus Infection C0085293?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
World Health Organization. Guidelines on Hepatitis E Virus Infection Prevention and Control. Hepatology International. 2022.
Kamar N, Dalton HR, Abravanel F, Izopet J. Hepatitis E Virus Infection. Clinical Microbiology Reviews. 2014.
Peron JM, Dalton HR, Izopet J, Mrani S. Real-World Effectiveness of Ribavirin in Acute Hepatitis E: A Multicenter European Study. Journal of Viral Hepatitis. 2021.
Bunchorntavakul C, Chotiyaputta W, Vajdic K. Hepatitis E in Immunocompromised Patients: Systematic Review and Meta-Analysis. Clinical Infectious Diseases. 2023.
Medication Comparisons
Compare medications used to treat Hepatitis E Virus Infection C0085293. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy