Hereditary Factor X Deficiency Disease C0272327
A rare inherited bleeding disorder from deficiency of Factor X, affecting both sexes equally. Treated with Factor X replacement through plasma or concentrates to manage bleeding episodes.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intracranial hemorrhage
Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Mucosal bleeding
(hematologic)Prolonged bleeding after injury
(hematologic)Joint pain (hemarthrosis)
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Factor X concentrate
Purified or recombinant factor X replacement therapy administered intravenously to correct deficiency and prevent or treat bleeding episodes. Provides specific replacement with minimal volume.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Fresh frozen plasma transfusion
Plasma containing functional factor X and other clotting factors transfused to treat bleeding or cover surgical procedures when specific concentrates are unavailable.
Additional treatment options
Prothrombin complex concentrate
Contains factors II, VII, IX, and X along with natural anticoagulants, providing broader hemostatic coverage for bleeding episodes or perioperative management.
medicationBleeding precautions and emergency planning
Implementing comprehensive safety measures including wearing medical alert identification, avoiding NSAIDs and anticoagulants, and establishing emergency care protocols with local hospitals.
lifestylePhysical therapy for joint health
Specialized exercise program designed to maintain joint mobility, strengthen supporting muscles, and prevent complications from bleeding into joints or muscles, improving functional outcomes.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hereditary Factor X Deficiency Disease C0272327?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Hereditary Factor X Deficiency Disease C0272327. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy