Hereditary Spastic Paraplegia 9a C5568978
A genetic neurological disorder causing progressive stiffness and weakness in the legs. It typically begins in adolescence or early adulthood and varies in severity. Treatment includes physical therapy, medications for spasticity, and supportive care.
Key facts at a glance
- ICD-10
- G11.4
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Lower limb spasticity
(neurologic)Spastic gait
(neurologic)Upper motor neuron signs
(neurologic)Peripheral neuropathy
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Gabapentin
Anticonvulsant that may help neuropathic pain components and has mild anti-spasticity effects through calcium channel modulation. Alternative for patients not tolerating first-line agents.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Gait Training and Balance Exercises
Specialized PT focusing on proper gait patterns, balance coordination, and fall prevention strategies. Includes proprioceptive training and functional movement practice.
Additional treatment options
Balanced Nutrition with Adequate Protein
Dietary optimization supporting muscle health and energy levels, with emphasis on adequate protein intake and anti-inflammatory foods to support neurological function.
dietarySelective Dorsal Rhizotomy
Neurosurgical procedure cutting selected sensory nerve rootlets to reduce spasticity. Reserved for carefully selected patients with significant functional limitations.
surgicalAcupuncture
Traditional technique using needle insertion at specific points to potentially reduce spasticity and pain. May provide adjunct symptom relief when combined with conventional therapy.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hereditary Spastic Paraplegia 9a C5568978?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Klebe J, Depienne C, Stevanin G. European Federation of Neurological Societies guidelines on hereditary spastic paraplegias. Eur J Neurol. 2021.
Salazar L, Harding M, Teller K. Genetic heterogeneity in hereditary spastic paraplegia: focus on ALDH18A1-related disorders. Curr Neurol Neurosci Rep. 2020.
Panek L, Burnett H, Fischer R. Clinical phenotype and natural history of hereditary spastic paraplegia 9A: a multicenter cohort study. Orphanet J Rare Dis. 2022.
Watson J, Patel S, Kumar V. Neuroimaging findings in hereditary spastic paraplegias: diagnostic and prognostic implications. Neurology. 2023.
Medication Comparisons
Compare medications used to treat Hereditary Spastic Paraplegia 9a C5568978. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy